Certified Reference Materials (CRMs) are an integral part of these QA/QC tools. traceability can be established by calibrating with a natural-matrix material. However, by definition, the traceability chain for natural-matrix materials has at least one more link than that of a calibration material and so will not provide the smallest

Reference material accompanied by a certificate, one or more of whose property values are certified by a procedure which establishes its traceability to an accurate realisation of the unit in which the property values are expressed, and for which each certified value is accompanied by an uncertainty at a stated level of confidence. ECRM

These certified reference materials are traceable to the original culture and have confirmed identity, well-defined characteristics, 

Certified Reference Materials (CRMs) are 'controls' or standards used to check the quality and traceability of products. A reference standard for a unit of measurement is an artifact that embodies the quantity of interest in a way that ties its value to the reference base for calibration.. At the highest level, a primary reference standard is assigned a value by direct comparison with the

NOTE 2 Procedures for the production and certification of certified reference materials are given, e.g. in ISO Guide 34 and ISO Guide 35. NOTE 3 In this definition, "uncertainty" covers both 'measurement uncertainty' and 'uncertainty associated with the value of a nominal property ', such as for identity and sequence.

With the Certified Reference Material (CRM) or Reference Material grade comes the Certificate of Analysis (CoA). Within the CoA, there are several quality parameters which are critical to understand: accuracy, consistency, homogeneity, purity, and stability. Also, what is being certified is important to understand – namely, the certified

1) The definition of a reference material certificate is given later. (2) CRMs are generally prepared in batches for which the property values are.

A certified reference material is required for any laboratory operating within the ISO 17025 guidelines. The ISO accreditation of a CRM 

Certified Reference Materials, as defined in the ISO Guide 30 and the International Vocabular of Metrology Note 5 VIM has an analogous definition (ISO/IEC Guide 99:2007, 5.13), but restricts the term "measurement" to apply to quantitative values and not to

certified reference material. [ ′sərd·ə‚fīd ′ref·rəns ¦mə′tir·ē·əl] (analytical chemistry) A reference material, one or more of whose property values are certified by a technically valid procedure, for which a certificate or other documentation has been issued by an appropriate certifying agency.

We offer a wide range of Certified Reference Materials (CRMs) for testing applications including forensic and clinical toxicology analysis, diagnostic testing, therapeutic drug monitoring,